In a decision announced today (March 26), the U.S. Patent and Trademark Office’s Patent Trial and Appeal Board (USPTO and PTAB, respectively) reaffirmed its original decision that the Broad Institute, ...
Horses created with the help of the CRISPR–Cas9 gene-editing technique have sparked controversy in the world of polo. Plus, air pollution is linked to a form of dementia and a newfound immune cell in ...
A new research paper is stirring up controversy among scientists interested in using DNA editing to treat disease. In a two-page article published in the journal Nature Methods on May 30, a group of ...
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double ...
Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein and endothelial lipases. ANGPTL3 loss-of-function genetic variants are associated with decreased levels of low-density lipoprotein ...
Northwestern scientists have developed a new nanostructure that supercharges CRISPR’s ability to safely and efficiently enter cells, potentially unlocking its full power to treat genetic diseases. By ...
In 1959, French geneticist Jérôme Lejeune made a landmark discovery – Down syndrome was caused by the presence of an extra copy of chromosome 21. For over six decades since this revelation, our ...
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