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  1. Median lethal dose - Wikipedia

    In toxicology, the median lethal dose, LD50 (abbreviation for " lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given …

  2. CCOHS: What is a LD₅₀ and LC₅₀?

    Aug 28, 2025 · The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material. Toxicologists can use many kinds of animals but most often testing is …

  3. What Is an LD50 and Why Is It Important in Toxicology?

    Aug 21, 2025 · The LD50, or Lethal Dose 50%, is a standard measure in toxicology for the acute toxicity of a substance. This metric provides a quantitative estimate of a material’s short-term …

  4. Median Lethal Dose (LD50): Definition and Limitations | Biology …

    Feb 11, 2018 · The median lethal dose, or LD50, is a term used in toxicology as a measurement of a lethal dose of a substance (e.g., pathogen, medication, toxic substance, etc.). Specifically, …

  5. Understanding LD50 in Toxicology - numberanalytics.com

    Jun 14, 2025 · LD50, or the median lethal dose, is a crucial concept in toxicology that measures the toxicity of a substance. It is defined as the dose of a substance that is lethal to 50% of the …

  6. What is LD50?: A Comprehensive Guide to the Lethal Dose

    Dec 3, 2025 · Understand what is LD50 and its crucial role in pharmacology and toxicology. Explore its history, calculation, ethical concerns, and modern alternatives to acute toxicity testing.

  7. LD50 (Median Lethal Dose) | SpringerLink

    Jan 1, 2024 · The amount of a chemical agent that is expected to kill 50% of the test organisms when given directly under the test’s stated conditions. For many years, the gold standard for …

  8. 7.7.2 Evaluating Toxicity Data | Environment, Health and Safety

    The LD50 describes the amount of chemical ingested or absorbed by the skin in test animals that causes death in 50% of test animals used during a toxicity test study.

  9. 22.4: The Lethal Dose - Chemistry LibreTexts

    Describe the LD 50 value and its limitations. Know the LD 50 value of various substances. The LD 50 is a standardized measure for expressing and comparing the toxicity of chemicals. The LD …

  10. Lethal dose - Wikipedia

    The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose …